Phospholipid scramblases are proteins that facilitate the movement of phospholipids between the inner and outer leaflets of a cell membrane. This process is essential for maintaining membrane asymmetry and plays a crucial role in various cellular functions, including apoptosis and blood coagulation. These proteins operate in response to specific signals, allowing for the rapid redistribution of lipids. By disrupting the typical arrangement of phospholipids, scramblases help cells respond to stress or injury, promoting processes like cell signaling and wound healing. Their activity is vital for normal cellular function and overall health.