Phospholipase C (PLC) is an enzyme that plays a crucial role in cellular signaling. It is responsible for breaking down a specific type of lipid called phosphatidylinositol 4,5-bisphosphate (PIP2) found in cell membranes. This process generates two important signaling molecules: inositol trisphosphate (IP3) and diacylglycerol (DAG), which help transmit signals within the cell.
The activation of PLC is often triggered by various hormones and growth factors binding to their respective receptors on the cell surface. Once activated, PLC facilitates a cascade of intracellular events, leading to various cellular responses such as cell growth, differentiation, and metabolism.