Phospholipase C is an enzyme that plays a crucial role in cellular signaling. It is responsible for breaking down a specific type of lipid called phosphatidylinositol 4,5-bisphosphate (PIP2) found in cell membranes. This process generates two important signaling molecules: inositol trisphosphate (IP3) and diacylglycerol (DAG), which help transmit signals within the cell. The activation of Phospholipase C is often triggered by various receptors, such as G protein-coupled receptors (GPCRs). Once activated, the resulting IP3 can stimulate the release of calcium ions from the endoplasmic reticulum, while DAG activates protein kinase C (PKC). Together, these pathways influence numerous cellular functions, including growth, differentiation, and metabolism.