PMD, or Progressive Muscular Dystrophy, is a group of genetic disorders characterized by progressive weakness and degeneration of the skeletal muscles. These conditions are caused by mutations in genes responsible for muscle function, leading to muscle wasting and loss of mobility over time. Symptoms can vary widely, but they often include difficulty walking, muscle cramps, and fatigue. There are several types of PMD, including Duchenne Muscular Dystrophy and Becker Muscular Dystrophy, each with different onset ages and severity levels. Diagnosis typically involves genetic testing, muscle biopsies, and clinical evaluations. While there is currently no cure, treatments focus on managing symptoms and improving quality of life.