Neurofibromatosis Type 1
Neurofibromatosis Type 1 (NF1) is a genetic disorder that primarily affects the skin and nervous system. It is caused by a mutation in the NF1 gene, which leads to the growth of non-cancerous tumors called neurofibromas. People with NF1 often have café-au-lait spots, which are light brown skin patches, and may experience other symptoms like learning disabilities or bone deformities.
The condition is inherited in an autosomal dominant pattern, meaning only one copy of the mutated gene from a parent can cause the disorder. NF1 affects approximately 1 in 3,000 individuals worldwide, and while there is no cure, regular monitoring and treatment can help manage symptoms.