Malformation refers to an abnormality in the structure or shape of a body part, which can occur during development. These irregularities can affect various systems, including the skeletal, cardiovascular, or nervous systems, and may be present at birth or develop later in life. Causes of malformations can include genetic factors, environmental influences, or a combination of both. Some malformations are minor and may not require treatment, while others can lead to significant health issues and may necessitate medical intervention or surgery.