Luisa of Savoy was born on November 28, 1492, in Savigliano, Italy. She was a member of the House of Savoy and became the Duchess of Savoy through her marriage to Charles III of Savoy. Luisa played a significant role in the political landscape of her time, particularly in the affairs of the Duchy of Savoy. As a mother, Luisa was influential in the upbringing of her children, including Emmanuel Philibert, who later became the Duke of Savoy. She was known for her strong character and dedication to her family's legacy, contributing to the stability and prosperity of the duchy during her lifetime.