Kashin-Beck disease is a type of osteoarthropathy that primarily affects the joints and bones, leading to deformities and pain. It is most commonly found in certain regions of China, Russia, and Mongolia, where dietary deficiencies, particularly of selenium, are prevalent. The disease typically manifests in childhood and can result in stunted growth and joint problems. The exact cause of Kashin-Beck disease is not fully understood, but it is believed to be linked to environmental factors and nutritional deficiencies. It can lead to significant disability if not addressed, making early diagnosis and intervention important for affected individuals.