Isabel Neville was a notable figure in 15th-century England, born around 1451. She was the daughter of Richard Neville, the 16th Earl of Warwick, and Anne Beauchamp. Isabel became the Duchess of Clarence through her marriage to George Plantagenet, the brother of King Edward IV. Isabel played a significant role in the political landscape of her time, particularly during the Wars of the Roses. Her family was deeply involved in the conflict between the Lancastrians and Yorkists. Isabel's life was marked by the tumultuous events of this period, which ultimately led to her early death in 1476.