Interference Contrast
Interference contrast is a microscopy technique that enhances the visibility of transparent specimens, such as biological tissues or cells. It works by exploiting the differences in refractive index between the specimen and its surroundings, creating contrast through the interference of light waves. This method allows for detailed observation without the need for staining, preserving the natural state of the sample.
This technique is particularly useful in fields like biology and materials science, where it helps researchers study fine structures and cellular details. By using specialized optics, interference contrast can reveal features that are otherwise difficult to see with standard brightfield microscopy.