Infectious Salmon Anemia (ISA) is a viral disease that primarily affects farmed Atlantic salmon. It is caused by the Infectious Salmon Anemia Virus (ISAV), which can lead to significant economic losses in the aquaculture industry. The disease is characterized by symptoms such as anemia, lethargy, and increased mortality rates among infected fish. ISA is transmitted through direct contact between fish or through contaminated water and equipment. Effective management strategies, including biosecurity measures and vaccination, are essential to control the spread of the virus and protect fish populations in aquaculture settings.