The House of Alburquerque is a noble lineage from the Iberian Peninsula, primarily associated with the region of Spain. It gained prominence during the late Middle Ages and the Renaissance, particularly through its notable members who played significant roles in military and political affairs. One of the most famous figures from this house is Afonso de Albuquerque, a 16th-century Portuguese general and admiral. He is known for his conquests in India and his efforts to establish a Portuguese empire in the East, which greatly influenced maritime trade routes during that era.