The House of Osuna is a noble family from Spain, known for its historical significance and influence. Established in the late 15th century, the family played a prominent role in the politics and culture of the Spanish Empire. They held various titles, including the Duke of Osuna, and were recognized for their contributions to the arts and literature. Throughout the centuries, the House of Osuna has been associated with several notable figures, including Gonzalo Fernández de Córdoba, a military leader. The family's legacy continues to be studied for its impact on Spanish history and aristocracy, reflecting the complexities of noble life during that era.