Ebola is a severe viral illness caused by the Ebola virus, which can lead to high mortality rates. It is transmitted to humans through contact with bodily fluids of infected animals, such as fruit bats and primates, or through contact with infected individuals. Symptoms typically include fever, severe headache, muscle pain, and fatigue, followed by vomiting, diarrhea, and in some cases, internal and external bleeding. The first recognized outbreak of Ebola occurred in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, there have been several outbreaks in Africa, with the most significant one occurring in 2014-2016. Efforts to control the virus include isolation of patients, contact tracing, and vaccination, with the rVSV-ZEBOV vaccine showing promise in preventing the disease.