The title "Duke of Saxe" refers to a noble title associated with the region of Saxony in Germany. Historically, the Dukes of Saxe ruled various territories within this region, which played a significant role in the political landscape of medieval and early modern Europe. The title has been held by several notable figures, contributing to the cultural and political development of Germany. The most famous Duke of Saxe was John Frederick I, who ruled during the 16th century and was a key figure in the Reformation. The title has since evolved, and today, it is often associated with the historical legacy of the Saxon royal family and their influence on German history.