Cowden Disease
Cowden Disease is a rare genetic disorder characterized by the development of multiple noncancerous growths called hamartomas. These growths can appear on various parts of the body, including the skin, mucous membranes, and internal organs. Individuals with Cowden Disease have an increased risk of certain cancers, particularly breast cancer and thyroid cancer.
The condition is caused by mutations in the PTEN gene, which plays a crucial role in regulating cell growth. Diagnosis typically involves a combination of clinical evaluation, family history, and genetic testing. Early detection and regular monitoring are essential for managing the associated cancer risks.