Coagulation Factor IX is a protein that plays a crucial role in the blood clotting process. It is part of the intrinsic pathway of coagulation, which helps form clots to stop bleeding. Factor IX is produced in the liver and is activated by another protein called Factor XI. A deficiency in Coagulation Factor IX leads to a bleeding disorder known as Hemophilia B. This condition is inherited and primarily affects males. Treatment often involves infusions of synthetic or donated Factor IX to help manage bleeding episodes and prevent complications.