The intrinsic pathway is a crucial part of the body's blood coagulation process, which helps prevent excessive bleeding. It is activated when blood comes into contact with damaged blood vessel surfaces, leading to a series of reactions involving various proteins known as clotting factors. This pathway ultimately results in the conversion of prothrombin to thrombin, which plays a key role in forming a stable blood clot.
This pathway works alongside the extrinsic pathway, which is activated by external trauma. Together, they converge on a common pathway that leads to the formation of a fibrin mesh, securing the clot and promoting healing. Understanding the intrinsic pathway is essential for diagnosing and treating bleeding disorders.