CFTR modulators are a class of medications designed to improve the function of the CFTR protein, which is defective in individuals with cystic fibrosis. These drugs work by enhancing the protein's ability to transport chloride ions across cell membranes, helping to restore balance in salt and water levels in the lungs and other organs. There are different types of CFTR modulators, including correctors and potentiators. Correctors help the CFTR protein reach the cell surface, while potentiators increase its activity once it is there. Together, these treatments can significantly improve lung function and overall quality of life for patients with cystic fibrosis.