CFTR, or Cystic Fibrosis Transmembrane Conductance Regulator, is a protein that functions as a channel for chloride ions across cell membranes. It plays a crucial role in maintaining the balance of salt and water in various tissues, particularly in the lungs and digestive system. Mutations in the CFTR gene can lead to cystic fibrosis, a genetic disorder that causes thick, sticky mucus to build up in the lungs and other organs.
The CFTR protein is essential for proper respiratory function, as it helps to keep mucus thin and mobile, allowing for effective clearance of pathogens and debris. Treatments for cystic fibrosis often focus on improving CFTR function or managing symptoms, highlighting the importance of this protein in overall health.