Blistering diseases are a group of skin disorders characterized by the formation of blisters, which are fluid-filled sacs that develop on the skin or mucous membranes. These conditions can result from various causes, including autoimmune reactions, infections, or genetic factors. Common types include pemphigus vulgaris and bullous pemphigoid, both of which involve the immune system attacking the skin. Symptoms of blistering diseases often include painful blisters, redness, and itching. Diagnosis typically involves a physical examination and may require skin biopsies or blood tests to identify the underlying cause. Treatment options vary depending on the specific disease and may include medications to suppress the immune response or manage symptoms.