Pemphigus vulgaris is a rare autoimmune disorder that causes painful blisters and sores on the skin and mucous membranes. It occurs when the immune system mistakenly attacks proteins that help skin cells stick together, leading to the formation of blisters. These blisters can be fragile and may rupture easily, causing open sores that can become infected. The condition often starts in the mouth, making it difficult to eat or drink. Treatment typically involves medications that suppress the immune system, such as corticosteroids, to reduce inflammation and prevent new blisters from forming. Early diagnosis and management are crucial for improving quality of life.