The Binding of Isaac is a popular indie video game developed by Edmund McMillen. Released in 2011, it features a top-down, dungeon-crawling format where players control a young boy named Isaac. After his mother receives a message from God, she attempts to sacrifice him, prompting Isaac to escape into the basement, where he faces various monsters and challenges. The game is known for its roguelike elements, meaning each playthrough is different due to randomly generated levels and items. Players collect power-ups and face bosses, with the goal of defeating Mom and uncovering the game's deeper story.