The Banu Qaynuqa was one of the three main Jewish tribes in Medina during the time of the Prophet Muhammad. They were known for their skills in metalwork and trade, contributing to the economy of the city. The tribe had a strong presence and was involved in various alliances and conflicts with other tribes. In 624 CE, tensions arose between the Banu Qaynuqa and the Muslim community, leading to their eventual expulsion from Medina. This conflict was part of a broader struggle between the early Muslims and various tribes in the region, marking a significant moment in the history of Islam.