Alpha-Gal Syndrome is an allergic reaction to a carbohydrate called alpha-gal, found in red meat and other animal products. This condition often develops after a person is bitten by a tick, particularly the Lone Star tick, which can transfer the alpha-gal molecule into the bloodstream. Symptoms may include hives, gastrointestinal issues, and even anaphylaxis, typically occurring several hours after consuming meat. Diagnosis usually involves a blood test to check for specific antibodies against alpha-gal. Management primarily includes avoiding red meat and products containing alpha-gal. Awareness of this syndrome is crucial, especially in areas where tick bites are common.