ABCC2
ABCC2, also known as the Multidrug Resistance Protein 2 (MRP2), is a protein encoded by the ABCC2 gene in humans. It plays a crucial role in the transport of various substances across cell membranes, particularly in the liver, kidneys, and intestines. This protein helps in the excretion of drugs, toxins, and metabolites, contributing to the body's ability to eliminate harmful compounds.
Mutations or dysfunctions in the ABCC2 gene can lead to various health issues, including drug resistance and certain diseases like Dubin-Johnson syndrome. Understanding ABCC2 is important for pharmacology and toxicology, as it influences how the body processes medications and other substances.