Piperina is a natural compound found in black pepper, specifically in the fruit of the Piper nigrum plant. It is responsible for the pungent flavor of black pepper and has been studied for its potential health benefits, including anti-inflammatory and antioxidant properties. Research suggests that piperina may enhance the bioavailability of certain nutrients and drugs, meaning it can help the body absorb them more effectively. This property makes it a subject of interest in dietary supplements and herbal medicine, where it is often combined with other compounds to improve their effectiveness.