The neurokinin-3 receptor (NK3R) is a protein found in the brain and other tissues that plays a crucial role in regulating various physiological functions. It is part of the neurokinin family of receptors, which respond to specific signaling molecules called neurokinins. NK3R is primarily activated by neurokinin B, influencing processes such as mood, stress response, and reproductive functions. Research on NK3R has gained attention for its potential implications in treating conditions like depression, anxiety, and hormonal disorders. By understanding how NK3R works, scientists hope to develop new therapies that target this receptor to improve mental health and hormonal balance.