The Neurokinin-2 receptor (NK2R) is a protein found in the body that plays a crucial role in the nervous system. It is part of the tachykinin family of receptors and primarily binds to the neuropeptide neurokinin A. This interaction is important for various physiological processes, including the regulation of smooth muscle contraction and the modulation of pain. NK2R is distributed in several tissues, including the lungs and gastrointestinal tract, where it influences functions such as bronchoconstriction and gut motility. Research on NK2R is ongoing, as it may have implications for treating conditions like asthma and gastrointestinal disorders.