Natural progesterone is a hormone produced by the ovaries in women and the adrenal glands in both men and women. It plays a crucial role in regulating the menstrual cycle, supporting pregnancy, and maintaining overall hormonal balance. Natural progesterone can also be found in certain plants, such as wild yam, and is often used in hormone replacement therapy. In addition to its reproductive functions, natural progesterone has been studied for its potential effects on mood, sleep, and bone health. It is available in various forms, including creams, capsules, and injections, and is sometimes prescribed to alleviate symptoms of menopause or premenstrual syndrome (PMS).