Gelatinases are a type of enzyme that break down gelatin and collagen, which are proteins found in connective tissues. They belong to a larger family of enzymes known as matrix metalloproteinases (MMPs). Gelatinases play a crucial role in various biological processes, including tissue remodeling, wound healing, and the development of certain diseases. There are two main types of gelatinases: MMP-2 and MMP-9. These enzymes are produced by various cells in the body, including fibroblasts and immune cells. Abnormal activity of gelatinases can contribute to conditions such as cancer metastasis and inflammatory diseases, making them important targets for medical research and potential therapies.