Loop diuretics are a class of medications that help the body remove excess fluid by increasing urine production. They work by inhibiting the reabsorption of sodium and chloride in the loop of Henle, a part of the kidney. This action leads to a decrease in blood volume and can help manage conditions like heart failure, hypertension, and edema. Common examples of loop diuretics include furosemide and bumetanide. These medications are often prescribed when other diuretics are ineffective. While they are effective in reducing fluid overload, they can also lead to electrolyte imbalances, so monitoring is essential during treatment.