Junctional EB, or junctional epidermolysis bullosa, is a rare genetic skin disorder characterized by fragile skin that blisters easily. This condition occurs due to mutations in genes responsible for producing proteins that help anchor the skin layers together. As a result, even minor friction or trauma can lead to painful blisters and sores. Individuals with junctional EB may experience symptoms from birth, including widespread blistering and skin erosion. The severity of the condition can vary, and complications may include infections and scarring. Management typically focuses on wound care and preventing infections to improve quality of life for those affected.