Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a genetic condition caused by mutations in the FH gene. Individuals with HLRCC are at an increased risk of developing leiomyomas, which are benign tumors of smooth muscle, often found in the skin and uterus. They also have a higher likelihood of developing renal cell carcinoma, a type of kidney cancer. This condition is inherited in an autosomal dominant pattern, meaning that only one copy of the mutated gene from an affected parent can lead to the disease in their children. Early detection and monitoring are crucial for managing the risks associated with HLRCC.