The FH gene (Fumarate Hydratase) is a gene that provides instructions for making a protein involved in the body's energy production. This protein plays a crucial role in the citric acid cycle, which helps convert food into energy. Mutations in the FH gene can disrupt this process, leading to various health issues. Mutations in the FH gene are associated with a rare genetic condition known as Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC). Individuals with HLRCC may develop benign tumors in the skin and uterus, as well as an increased risk of certain types of kidney cancer. Early detection and monitoring are essential for managing these risks.