Glucose-dependent insulinotropic polypeptide (GIP) is a hormone produced in the intestines that plays a key role in regulating blood sugar levels. It is released in response to food intake, particularly when carbohydrates and fats are consumed. GIP stimulates the pancreas to release insulin, which helps lower blood sugar levels by facilitating the uptake of glucose into cells. In addition to its insulin-releasing effects, GIP also influences fat metabolism and may promote fat storage. Research has shown that GIP can affect appetite and energy balance, making it an important factor in understanding conditions like obesity and type 2 diabetes.