Glucose-dependent insulinotropic polypeptide (GIP) is a hormone produced in the intestines that plays a key role in regulating blood sugar levels. It is released in response to food intake, particularly when carbohydrates and fats are consumed. GIP stimulates the pancreas to release insulin, which helps lower blood glucose levels. In addition to its insulin-releasing effects, GIP also influences fat metabolism and may promote fat storage. It is part of a group of hormones known as incretins, which enhance insulin secretion in a glucose-dependent manner, meaning they work more effectively when blood sugar levels are elevated.