Fibrates are a class of medications primarily used to lower triglyceride levels in the blood and increase high-density lipoprotein (HDL) cholesterol. They work by activating a specific receptor in the body that helps break down fats and improve lipid profiles. Common fibrates include fenofibrate and gemfibrozil. These medications are often prescribed for individuals at risk of cardiovascular diseases due to high triglyceride levels. While fibrates can be effective, they may also have side effects, such as gastrointestinal issues or muscle pain, and should be used under medical supervision, especially when combined with other cholesterol-lowering drugs like statins.