extrusion-spheronization
Extrusion-spheronization is a pharmaceutical process used to create spherical pellets from powdered materials. It involves two main steps: extrusion, where the powder is forced through a die to form long strands, and spheronization, where these strands are cut and rounded into small, uniform pellets. This method helps improve the flow and dissolution properties of the final product.
The resulting pellets can be used in various applications, including controlled-release formulations and taste masking. By ensuring consistent size and shape, extrusion-spheronization enhances the efficiency of drug delivery systems, making medications more effective and easier to manufacture.