depolarizing neuromuscular blockers
Depolarizing neuromuscular blockers are a type of medication used to induce muscle relaxation during surgical procedures or mechanical ventilation. They work by binding to the acetylcholine receptors on muscle cells, causing an initial muscle contraction followed by paralysis. This effect is temporary and allows for easier intubation and surgical access.
One common example of a depolarizing neuromuscular blocker is succinylcholine. It is rapidly broken down by the enzyme pseudocholinesterase, leading to a short duration of action. These medications are typically used in controlled medical settings due to potential side effects, such as increased potassium levels and muscle pain.