Chylomicronemia syndrome is a rare genetic disorder characterized by the accumulation of chylomicrons, which are lipoproteins that transport dietary fats in the bloodstream. This condition occurs when the body cannot effectively break down fats due to deficiencies in specific enzymes, leading to high levels of triglycerides in the blood. Symptoms may include abdominal pain, pancreatitis, and skin lesions known as eruptive xanthomas. Management of chylomicronemia syndrome typically involves dietary changes, such as a low-fat diet, and medications to lower triglyceride levels. Regular monitoring by healthcare professionals is essential to prevent complications, including pancreatitis and cardiovascular issues.