Beta-sarcoglycan is a protein that plays a crucial role in maintaining the structural integrity of muscle cells. It is part of a larger complex known as the dystrophin-glycoprotein complex, which helps connect the muscle cell membrane to the underlying cytoskeleton. This connection is essential for muscle function and stability. Mutations in the gene that encodes beta-sarcoglycan can lead to various forms of muscular dystrophy, particularly sarcoglycanopathies. These conditions result in progressive muscle weakness and degeneration, highlighting the importance of this protein in muscle health and function.