Alkaline ceramidase is an enzyme that plays a crucial role in the metabolism of lipids, specifically in the breakdown of ceramides. Ceramides are fatty molecules found in cell membranes, and their regulation is important for maintaining skin health and barrier function. This enzyme operates optimally at an alkaline pH, which is why it is named "alkaline" ceramidase. The activity of alkaline ceramidase is significant in various biological processes, including cell signaling and inflammation. Dysregulation of this enzyme can lead to skin disorders and other health issues. Research into alkaline ceramidase may provide insights into potential treatments for conditions related to lipid metabolism, such as eczema and psoriasis.