Aldolase A is an enzyme that plays a crucial role in the glycolysis pathway, which is the process that breaks down glucose to produce energy. Specifically, it catalyzes the conversion of fructose 1,6-bisphosphate into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. This reaction is essential for energy production in cells. Aldolase A is primarily found in muscle and brain tissues, where it helps meet the high energy demands of these organs. Mutations in the ALDOA gene, which encodes this enzyme, can lead to glycogen storage diseases and other metabolic disorders, highlighting its importance in human health.