Zinc metalloproteases are a type of enzyme that require zinc ions to function. They play a crucial role in various biological processes, including protein degradation, cell signaling, and tissue remodeling. These enzymes are found in many organisms, from bacteria to humans, and are involved in important physiological functions. These metalloproteases are characterized by their ability to cleave peptide bonds in proteins. They are essential in processes such as apoptosis, immune response, and extracellular matrix turnover. Dysregulation of zinc metalloproteases can lead to various diseases, including cancer and inflammatory disorders.