The Wytheville Historic District is located in Wytheville, Virginia, and features a collection of well-preserved buildings that reflect the town's rich history. Established in the 19th century, the district showcases various architectural styles, including Victorian, Federal, and Greek Revival. Designated as a historic district, it includes notable sites such as the Wythe County Courthouse and several historic homes. The area is recognized for its cultural significance and is listed on the National Register of Historic Places, making it an important destination for those interested in American history and architecture.