Wnt Signaling Pathway
The Wnt signaling pathway is a complex network of proteins that plays a crucial role in regulating cell growth, development, and differentiation. It is essential for various biological processes, including embryonic development and tissue homeostasis. When Wnt proteins bind to their receptors on the cell surface, they initiate a cascade of events that can influence gene expression in the nucleus.
This pathway can be divided into two main branches: the canonical pathway, which involves the stabilization of β-catenin, and the non-canonical pathway, which operates independently of β-catenin. Dysregulation of the Wnt signaling pathway is associated with several diseases, including cancer, making it a significant area of research in developmental biology and medicine.