β-catenin is a protein that plays a crucial role in cell signaling and the regulation of gene expression. It is part of the Wnt signaling pathway, which is important for various developmental processes and maintaining tissue homeostasis. When Wnt proteins bind to their receptors on the cell surface, β-catenin accumulates in the cell and translocates to the nucleus, where it influences the activity of specific genes. In addition to its role in signaling, β-catenin is also involved in cell adhesion. It interacts with cadherins, which are proteins that help cells stick together, forming tissues. Abnormal regulation of β-catenin can lead to various diseases, including cancer, highlighting its importance in both normal and pathological conditions.