William Worrall Mayo was a prominent American physician and surgeon, best known for co-founding the Mayo Clinic in Rochester, Minnesota. Born on July 29, 1819, in England, he immigrated to the United States in 1846, where he established a successful medical practice. His dedication to patient care and innovative medical practices laid the groundwork for what would become one of the world's leading healthcare institutions. Mayo's contributions to medicine extended beyond his practice; he emphasized the importance of collaboration among healthcare professionals. He worked closely with his sons, William James Mayo and Charles Horace Mayo, to develop the clinic's mission of providing high-quality, patient-centered care.