Charles Horace Mayo was an American physician and surgeon, born on June 19, 1865, in Rochester, Minnesota. He co-founded the Mayo Clinic with his brothers, William Worrall Mayo and Charles Mayo, which became a leading medical institution known for its innovative practices and patient-centered care. Mayo was a pioneer in the field of surgery and contributed significantly to the development of modern surgical techniques. He emphasized the importance of collaboration among medical professionals, which helped establish the Mayo Clinic as a model for integrated healthcare. He passed away on May 26, 1939.